Background Diabetes mellitus, as well as subsequent ocular complications such as cystoid macular edema (CME), are of fundametal socio-economic relevance. Therefore, we evaluated the influence of internal limiting membrane (ILM) removal on longterm morphological and functional outcome in patients with diabetes mellitus (DM) type 2 and chronic CME without evident vitreomacular traction.
Forty eyes with attached posterior hyaloid were included in this prospective trial and randomized intraoperatively. Prior focal (n=31) or panretinal (n=25) laser coagulationwas permitted. Group I (n=19 patients) underwent surgical induction of posterior vitreous detachment (PVD), group II (n=20 patients) PVD and removal of the ILM. Eleven patients with detached posterior hyaloid (group III) were not randomized, and ILM removal was performed. One eye had to be excluded from further analysis. Examinations included ETDRS best-corrected visual acuity (BCVA), fluorescein angiography (FLA) and OCT at baseline, 3 and 6 months postoperatively. Main outcome measure was BCVA at 6 months, secondary was foveal thickness.
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Sources: Hans Hoerauf, Anne Brüggemann, Manuela Muecke, Julia Lüke, Maya Müller, Einar Stefánsson, Hans-Peter Hammes, Claudia Weiß